Influences of ectoderm and endoderm on heart differentiation in the newt☆
[摘要] PresumptiveheartmesodermfromearlyneurulaeofthenewtTarichatorosawasisolatedaloneinsaltsolutionorwascombinedinexplantswithectoderm,orectodermandendoderm,fromvariousregionsoftheembryo.Thepresumptiveheartmesodermformedabeatingheartwhenisolatedaloneinonly14%ofthecases.Whenexplantedincombinationwithanteriorpresumptiveepidermis,beatingheartsdevelopedinaboutone-thirdofthecases.Beatingheartsformedinallexplantsofpresumptiveheartmesodermcombinedwithanteriorpresumptiveepidermisandendodermfromthefutureheartregion,andintwo-thirdsofthecasesiftheendodermcamefrommoredorsalorposteriorregions.Intheserieswheretheendodermwastestedfromthedorsalorposteriorregions,allexplantsthatfailedtoproducebeatingheartscontainedneuraltissuethathaddifferentiatedfromthepresumptiveepidermiswhereaseachexplantthatformedaheartlackedneuraltissue.Innocasedidabeatingheartdevelopfrompresumptiveheartmesoderminanexplantthatincludedpartoftheanteriorneuralplateandfoldaswellasanteriorpresumptiveepidermis.Heartsfailedtodevelopintheseexplantsevenwhenendodermfromthefutureheartregionwasadded.Endodermlessanimalsfailedtoproducehearts,butendodermlessanimalsalsodeprivedoftheirneuralplateandfolddidproducehearts.Itisconcludedthatbothectodermandendodermcaninfluencethedifferentiationofthepresumptiveheartmesoderm.Heartformationissuppressedbyanteriorneuralplateandfold,butisstimulatedbyendoderm.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
