Morphogenetic interactions in the development of the mouse thymus gland☆
[摘要] 1.1.Morphogenesisof12-daymouseembryothymusglandshasbeenanalyzedbyinvitroandtransplantationmethods.2.2.Ataglass-clotinterfacetheglandgrowsandundergoescharacteristiclobulation,butremainspredominantlyepithelial.Intransplantstotheanteriorchamberofadultmouseeyesitgrowsprofuselyandbecomeslymphoidal.3.3.Theglandmaybeseparatedintoepithelialandmesenchymalportionsbytheuseoftrypsin.Neithercomponentcandevelopinisolation,invitroorinvivo,butclusteringofthetwotissuesleadstotherestorationofthemorphogeneticsystem,withresultantinvitrolobulationandtheinvivoformationoflymphoidaltissue.4.4.Mesenchymefromavarietyofembryonicrudimentscanexertamorphogeneticeffectinvitro,thespecificpatternoftheepithelialresponsevaryingwiththesourceofmesenchymeused.Themesenchymalinfluencecanbeexertedacrossa20μmilliporefilterbarrier.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
