The content of pyridine dinucleotides in the mouse embryo before implantation☆
[摘要] Nicotinamideadeninedinucleotide(NAD)contentwasfoundtodecreaseinmouseembryosduringcleavageandtoincreaseagainattheblastocyststage.ThefirstenzymeinvolvedinbiosynthesisofNADfromnicotinamideisnicotinamidemononucleotide(NMN)-pyrophosphorylase.Nosuchenzymaticactivitywasfoundintheembryos,butNAD-glycohydrolaseactivitywasrelativelyhigh24–48hoursafterconception.Enzymeactivitydecreasedintheblastocyst.Theresultsarerelevanttounderstandingtheregulationofmetabolisminpreimplantationembryos.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
