Chromosome complements of Rana pipiens embryos developing from eggs injected with protein from adult liver cells☆
[摘要] FertilizedeggsofRanapipienswereinjectedwithvariousamountsofproteinextractedfromadultlivercellsofthesamespecies.Suchinjectedembryosgenerallyexhibiteddevelopmentalarrestatthelateblastulastage.Previousworkshowedthatnucleiofsuchembryoshadbeenirreversiblychangedsothattheycouldpromotedevelopmentonlytothebeginningofgastrulationwhentransplantedtoenucleatedeggs.Inthepresentstudychromosomeanalysesweremadeatsuccessivestagesinthedevelopmentofinjectedembryos.Theseanalysesrevealedthepresenceofchromosomalabnormalitiessuchasrings,fragments,andlossofchromosomesinalargeproportionofcellsinstagespriortoarrest.Thesechromosomalabnormalitiesmayreasonablybeinvokedasasufficientcauseforthearrestofdevelopment.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]