Nerve fiber requirements for regeneration in forelimb transplants of the newt Triturus☆
[摘要] Thedependenceoflimbregenerationonthenumberofnervefibersattheamputationsurfacewasexaminedfurtherinstudiesofthenerverequirementsforregenerationintransplantsoftheupperarmtotheback.Intime,thegraftswerereinnervatedbylocalfibersandinsomeoftheexperimentsbybrachialnervesthatweredeviatedtothesiteoftransplantation.Countsofnervefibersattheoriginalregeneratingsurfaceofthegraftshowedthatfarfewerfiberscaninducegrowththanarerequiredforregenerationofthenormallimb.Therefore,thethresholdnerverequirementsforregenerationarenotfixedbutvarywiththecapacityofthewoundtissuetorespondtonervousstimulation.Theabilitytorespondisincreasedinthewouldtissuesofthegraftpresumablybythetraumaoftransplantation.Theroleofthewoundtissuesinestablishingthethresholdnerverequirementsandpossiblyincontributingsubstancesimportantforregenerationarediscussed.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
