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Clonal analysis of determination dynamics in cultures of imaginal disks in Drosophila melanogaster☆
[摘要] SinglecellsweremarkedgeneticallybyX-ray-inducedsomaticcrossingoverorsomaticmutationinantennaldisksofDrosophilalarvae.Theirradiateddiskswereculturedinadultfemalehosts,wherethemarkedcellgivesrisetoaclone.Afterretransplantationintoalarvalhostthedifferentiationofsuchcloneswasanalyzed.Itisshownthatchangesindetermination(transdetermination)canoccurinsuchcellclones.Thus,presumptivepalpcellswhichnormallyproducetheirowntypeofcellsbycellheredity,maygiverisetowingcells(allotypicelements).Presumptivecellsofthearistaandthethirdantennalsegmentmayproducetarsalcells,whereastheanlageofthesecondsegmentrarelyformsanyallotypicelements.Eachtransdeterminationfromonecelltypetoanotheroccurswithadefiniteprobability.Duringproliferationagroupofcellsmayundergothesametypeoftransdeterminationsynchronously.
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[效力级别]  [学科分类] 生物科学(综合)
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