Clonal analysis of determination dynamics in cultures of imaginal disks in Drosophila melanogaster☆
[摘要] SinglecellsweremarkedgeneticallybyX-ray-inducedsomaticcrossingoverorsomaticmutationinantennaldisksofDrosophilalarvae.Theirradiateddiskswereculturedinadultfemalehosts,wherethemarkedcellgivesrisetoaclone.Afterretransplantationintoalarvalhostthedifferentiationofsuchcloneswasanalyzed.Itisshownthatchangesindetermination(transdetermination)canoccurinsuchcellclones.Thus,presumptivepalpcellswhichnormallyproducetheirowntypeofcellsbycellheredity,maygiverisetowingcells(allotypicelements).Presumptivecellsofthearistaandthethirdantennalsegmentmayproducetarsalcells,whereastheanlageofthesecondsegmentrarelyformsanyallotypicelements.Eachtransdeterminationfromonecelltypetoanotheroccurswithadefiniteprobability.Duringproliferationagroupofcellsmayundergothesametypeoftransdeterminationsynchronously.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]