A clonal system of differential gene activity in Drosophila☆
[摘要] Thepatternsofeyepigmentvariegationintwocasesofpositioneffect(oneinDrosophilavirilisandtheotherinD.melanogaster)wereshowntobelaiddownintheimaginaleyediskduringtheendofthefirstlarvalinstar.ThetimingofthisdeterminativeeventwasmadepossiblebycomparingthevariegationpatternswiththesizeandshapeoftwinspotsintheadulteyeformedbytheX-rayinductionofsomaticexchangeattheendofthefirstinstar.InD.virilisthevariegationpatternsandthetwinspotswerecomparedindifferentflies;whereas,inD.melanogaster,aschemewasdevisedsothatthecomparisoncouldbemadeinoneandthesameeye.Thevariegationpatternwasshowntobeclonal;therefore,theinformationcontainedinthisdeterminativeeventwaspassedontothedaughtersomaticcellsforanumberofcellgenerationsuntilthedifferentiationoftheeyewascompleteandpigmentsynthesisinitiated.AlthoughgrowthwasmarkedlyinhibitedinlarvaefedonmediumcontainingactinomycinDduringthefirstinstar,suchtreatmentdidnotaffectthepatternofposition-effectvariegation.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
