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Effects of specific prostaglandins on development of chick embryo skin and down feather organ, in vitro☆
[摘要] Twoprostaglandins,PGE1andPGE1-278,derivativesoffattyacids,whenappliedinculturetobackskinofthechickembryo,stimulateepidermalproliferationandkeratinization.Developmentofthedownfeatherorganiscompletelyblocked.Nohistochemicaldifferenceswerefoundbetweentreatedandcontrolskinswhichcouldbeattributedtotreatmentofthetissuesbytheprostaglandins.TheeffectsareequivocalinculturesusingembryonicextractorWaymouth's752chemicallydefinedmedium.Chemicalspecificityisindicatedbythefactthatadditionalcompoundsincludingthreeotherprostaglandins,norepinephrine,andlinoleicacidproducenoeffectsontheculturedskins.
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[效力级别]  [学科分类] 生物科学(综合)
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