Compression of Three Different Methods (Subjective Global Assessment, Bioelectric Impedance Analysis and Biochemical Indices) In Assessing Nutritional Status in Pediatric and Young Adult with Chronic Kidney Disease

[摘要] BackgroundandObjective:Protein-energymalnutrition(PEM)isoneofthemostprevalentprobleminrenalpatientsthatcandecreasequalityoflifeandincreasemortalityinthesepatients.Theaimofthisstudywastocomperethreedifferentmethodsofnutritionalassessmentforevaluationthenutritionalstatusofthesepatients.SubjectsandMethods:Inthisstudy,30pediatricpatientswithchronickidneydisease(6to20years)withGFR=15-60ml/min/1.72m2wereselectedandcomparedwith30healthycontrolsubjects.Nutritionalassessmentwasmadebyuseofsubjectiveglobalassessment(SGA),measuringserumalbumin,pre-albumin,IGF-Iandbodycompositionanalysisperformedbybioelectricimpedanceanalysis(BIA)method.ThedatawereanalyzedusingSPSSsoftware,normallydistributedvariableswereexpressedasmean±StandardDeviation(SD)andwerecomparedbyIndependentStudent’st-test.meanswereconsideredsignificantlydifferentatPlt;0.05.Results:BasedonSGAscorenoneofCKDpatientshadseveremalnutrition.MeanalbuminandIGF-1level,weresignificantlylowerinCKDchildren.BIAresultsshowedpatientswithCKDhadsignificantlylowerdryleanweight,bodycellmass,bodymassindexandbasalmetabolicrate.Conclusion:TheresultofpresentstudyshowedBIAcomparedwithSGAandbiochemicalfactorsismoreeffectiveinearlydetectionofmalnutritioninCKDchildren.ThereforethisstudysuggeststhatBIAcanbeanattractiveclinicaltooltodetectmalnutritioninCKD.

[学科分类] 基础医学