Effect of 12-Week Progressive Resistance Training on Balance, Fatigue and Disability in Women with MS

[摘要] BackgroundandObjective:MultipleSclerosis(MS)isademyelinatingdiseaseofthecentralnervoussystem(CNS)whichleadstomyelindistractionanddisfunctioninnerveconduction.Thepurposeofthisstudywastoevaluatetheeffectof12-weekprogressiveresistancetrainingonbalance,disabilityandfatigueinwomenwithMS.SubjectsandMethods:Basedonaquasiexperimentalmethod,24womenwithMS(30.5±5.9yearsold,68±11kg,height160±7.6cm)with1to4ExpandedDisabilityStatusScale(EDSS)degreeparticipatedandrandomlydividedintotwocontrolandexperimentalgroups.Experimentalgroupcarriedouta12-weekresistanceexerciseprogramfor45to60min3times/week.Controlgroupdidnotparticipateinanyroutineexerciseregimen.BergBalanceScaletest(BBS)wasusedtoassessmentofbalance.Inaddition,fatigueseverityscale(FFS)andEDSSquestionerswereusedtoevaluatefatigueanddisabilityrespectively.DatawereanalyzedbyMultipleAnalysesOfVariance(MANOVA)methodwithSPSSsoftwareatPlt;0.05.Results:Asignificantdifferenceinaveragescoresofbalanceandfatiguebetweencontrolandexperimentalgroups(Plt;0.05),However,nosignificantdifferencewasfoundinaveragescoresofEDSS(Pgt;0.05).Conclusion:12-weekresistancetrainingincreasesbalanceanddecreasesfatigueinMSpatient;however,hasnopositiveeffectondisability.

[学科分类] 基础医学