Comparison of Acoustic Features of High-Low vowels with Perceptual Speech Intelligibility in Normal and Adults with Parkinson

[摘要] BackgroundandObjecitve:Parkinson’sDisease(PD)isaprogressivediseaseresultingfromareductioninthereleaseofdopamine.Thislossofdopaminecanhaveaneffectonnon-speechmovements,aswellasvariousaspectsofspeechproduction.Dysarthriaisacollectivenameforagroupofspeechdisordersresultingfromdisturbanceinmuscularcontroloverthespeechmechanismduetodamagetothecentralorperipheralnervoussystem.Itproducesproblemsinoralcommunicationduetoparalysis,weaknessorincoordinationofthespeechmusculature.Asynthesisofresearchonnormalandneurologicallydisorderedspeechshouldleadtoanimprovedunderstandingoftheneuralregulationofspeech.SubjectsandMethods:Inthiscross-sectionalstudy,36voicesamplesinnormalvoicelessenvironmentwererecorded.FrequencydifferenceinhighandlowvowelswasmeasuredbyPraatsoftware.DataanalysiswasperformedbyIndependentSamplesTestandMaan-Whitenytests.Results:Allvariablesshowedsignificantdifferences.F1-F0inlowvowelsweresignificantlydecreasedinadultswithParkinson(Plt;0.001).F2-F1inhighvowelswassignificantlydecreasedinadultswithParkinson(Plt;0.05).Conclusion:TheresultsshowedthatParkinsondiseaseaffectsformantfrequency.

[学科分类] 基础医学