Antimicrobial Susceptibility Patterns of Salmonella Typhi From Ki-gali, Rwanda.
[摘要] Background:Salmonellosisisamajorhealthproblem,especiallyindevelopingcountrieslikeRwanda.Salmonellatyphiinfectsonlyhumanandhumantransmissionoccurthroughfeaco-oralroute.Moreover,speciesarebecomingresistanttothecommonlyusedantibiotics.Objective:TheaimofthepresentstudyistoknowantimicrobialsusceptibilitypatternswithspecialreferencetomultidrugresistanceSalmonellaentericaserovarTyphiandreducedsusceptibilitytonalidixicacidMaterialsandMethods:Atotal69S.typhiisolatedofKingFaisalhospital,Kigali,Rwandafromstoolandbloodspecimenswereincludedinthestudy.AntimicrobialsusceptibilitywasdonebyusingKirby-Bauerdiscdiffusionmethod.Results:TherewasdecreasedsusceptibilitywasobservedinChloramphenicol,Ampicillin,Amoxycillin/Calvvlanicacid,Tetracycline,CotrimoxazoleandNalidixicacid.Theseweresig-nificantincreaseinthemultidrugresistantsalmonellatyphi(MRST)from9.1%to25%re-spectivelybetween2007and2008.Alltheisolateswere100%sensitivetoCeftriaxone,LevofloxacinandCiprofloxacinConclusion:TyphoidfeverhasbeenendemicinKigali.Decreasedsusceptibilitytowardsnalidixicisobseveredwhichgivesusalarmfortreatmentfailuretowardsfluoroquinolones.Theantibioticsensitivitypatternischangingandresistantcasesareemergingduetoinap-propriateuseofantibiotics.
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[效力级别] [学科分类] 基础医学
[关键词] Antimicrobial susceptibility;Salmonella Typhi;Rwanda. [时效性]
