Evaluation of Insulin Resistance in Severe Preeclampsia.

[摘要] Introduction::thecauseofpreeclampsiahasnotbeenpreciselyunderstood.Oneofthereasons,asstatedbysome,mightberesistancetoinsulinhowever,theroleofinsulinresistanceinoccurrenceofpreeclampsiahasnotbeenprovensofar.Hence,theobjectiveofthisstudyistofindouttherelationshipbetweeninsulinresistanceandseverepreeclampsia.MaterialsandMethods::Inthiscase-controlstudy26healthypregnantwomenand26womenwithseverepreeclampsia,forwhomterminationofpregnancywasconcluded,wereincluded.Bothgroupsintermsofage,weight,parityandbodymassindex(BMI)wereidentical.Furthermore,FBSlevel,fastingbloodinsulinandresistancetoinsulinatthesamelaboratoryandbysimilarprocedureswereevaluatedforbothgroupsthroughoutthestudyanddocumentedinrelevantforms.ThedatawereanalyzedbySPSSsoftwareandPvalue#60;0.05wasconsideredsignificant.Results::TheresultsshowedthatthelevelofFBSwasnotsignificantlydifferentinpreeclampticpatientsandhealthypregnantcontrol(p=0.062).Moreoverwefoundthatthelevelsoffastinginsulinwassimilarwithintwogroups(P=0.80).Conclusion::Incurrentstudynorelevantwasobservedbetweenseverepreeclampsiaandresistancetoinsulin.

[学科分类] 基础医学

[关键词] Preeclampsia;Insulin resistance;Blood pressure disorders;Pregnancy