Comparative Study of Therapeutic Effects of Honey and Povidone Iodine in Surgical Wound Healing in Rabbit.

[摘要] Introduction:Durationandremainderscararetwoimportantproblemsinprocessofsurgicalwoundhealing,especiallyinlowmidlineincisionsthatusuallyhavemoredurationandwiderscarintheirhealingprocess.TheaimofthisstudywasacomparisonbetweenHoneyandPovidoneIodineinsurgicalwoundhealing,becauseofHoneyistheworld’soldestknownwounddressingandthereareseveralreportsfromitsantibacterialpropertiesandstimulatingeffectsonwoundhealingprocess.MaterialsandMethods:Thisclinicaltrialstudywasperformedon40femaleRabbitsthatwerenon-pregnant,5monthsagedwithaverageweightof1900grams,belongingtoAlbinorace,inAnimalInstituteinTehran,Iranintheyear2006.Forbeginning,Rabbitsweredividedintotwoequalgroupsrandomly,andthensimilarsurgicalincisions10cmtracedwereappliedafterappropriateshavingandlocalanesthesiaonexteriorareaofrightthighofallrabbits.ThenallRabbitswoundssuturedbySilk2.0separatelyandwerecoveredsimilarly.Coveringofwoundsintwogroupswerechangedevery12hoursandwoundsweredressedwith5mlofpurrednaturalHoneyinfirstgroupandinthesecondgroupirrigatedwith5mlofPovidoneIodine10%ineverytime.ThefindingswererecordedandanalyzedwithSPSSsoftwarebyusingofchi-squareandttest,p

[学科分类] 基础医学

[关键词] Honey;Povidone Iodine;surgical wound healing