The regulation and properties of Tn1/3 transposase

[摘要] Tn3 transposition is regulated at several levels. It is well established that resolvase, by binding at the res site, represses transcription of both tnpA and tnpR, which encode transposase and resolvase respectively. Binding of resolvase to res also leads to resolution of transposition cointegrates by site-specific recombination. In this work, translational fusions of tnpA and tnpR to lacZ have shown that at 30

[发布机构] University:University of Glasgow

[关键词] Genetics