The stereochemistry of hydrogen transfer from reduced nicotinamide–adenine dinucleotide phosphate in the reduction of ethylenic linkages during cholesterol biosynthesis

[摘要]

It is shown that during the saturation of steroid carbon–carbon double bonds at Δ^24,25 and Δ^14,15 the `hydride ion9 originates from the 4B side of the NADPH.