Albumin Excretion in Diabetes Mellitus

[摘要] Diabetes mellitus carries a twenty-fold excess mortality for insulin-dependent (IDDM) and two-fold for non-insulin dependent (NIDDM) patients compared with the nondiabetic population. Almost all of this excess is confined to those people who develop persistent proteinuria and is due mainly to cardiovascular and renal disease. In insulin-dependent diabetes, uraemia is common, whilst in non-insulin dependent diabetes, cardiovascular disease accounts for the majority of deaths. Once persistent proteinuria develops, progression of IDDM patients to end-stage renal disease is inevitable.

[发布机构] University:University of Glasgow

[关键词] Medicine