High-molecular-weight catecholamine–ATP aggregates are absent from the chromaffin-granule aqueous phase

[摘要]

Direct n.m.r. studies show that the viscous liquid phase which separates from solutions containing physiological concentrations of noradrenaline, ATP and Ca2+ is not present in the chromaffin-granule interior. This finding is verified for both adrenaline and noradrenaline by using 13C n.m.r. spectra.