GENETIC DISSECTION OF SEGREGATION DISTORTION. III. UNEQUAL RECOVERY OF RECIPROCAL RECOMBINANTS

[摘要] The genetic structure of a segregation distorter chromosome (a derivative of SD-36 ) has been analyzed in a system in which recombination in the second chromosome is blocked by inversions except for the critical region around the centromeric heterochromatin. The results confirm the map order and characteristics of four loci known to be involved in segregation distortion, namely Sd, E(SD), Rspins, M(SD) . However, SD-36 carries a fifth major locus involved in distortion. This locus is near pr in 2L and has the effect of enhancing the degree of distortion. In addition, reciprocal recombinant products from SD-36 are recovered unequally. All recombinants carrying the pr region from SD-36 seem also to carry Sd , although Sd has previously been mapped 1.6 units to the left of pr . Both the enhancement of distortion and the unequal recovery of reciprocal products can be explained if it is assumed that the new locus near pr in SD-36 is actually a duplication of Sd .

[学科分类] 医学（综合）