An Evaluation of Epithelial Membrane Antigen as a Target for Monoclonal Antibodies in the Investigation of Patients With Colorectal Cancer

[摘要] The Epithelial Membrane Antigen(EMA) is known to be strongly expressed by the majority of adenocarcinomas including those of the breast, ovary and colon and also weakly by a variety of normal glandular tissues. This antigen has not, however, been investigated specifically in colorectal cancer. This thesis investigates the clinical applications in colorectal cancer of a monoclonal antibody(MAb), labelled ICR2 after the Institute of Cancer Research, Sutton, Surrey, which recognises EMA.

[发布机构] University:University of Glasgow

[关键词] Medicine, Oncology