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THE GENETICS OF DROSOPHILA SUBOBSCURA POPULATIONS. V. A STUDY OF LINKAGE DISEQUILIBRIUM IN NATURAL POPULATIONS BETWEEN GENES AND INVERSIONS OF THE E CHROMOSOME
[摘要] The genetics of Hk and Est-9 complex gene have been studied in Drosophila subobscura . While Hk alleles mendelize normally, Est-9 is a complex locus consisting of several very closely linked genes with active and silent alleles. Both genes are located on chromosome E ; a detailed genetic map was constructed with the help of visible markers and inversions. Both Hk and Est-9 are included in or are very near to inversions of the E chromosome. While Hk does not show linkage disequilibrium either with Est-9 or inversions, Est-9 does show disequilibrium in two ways: both with inversions and between different Est-9 genes. All natural populations studied show the same kind of association between Est-9 gene combinations and inversions. It is argued that these results are better explained by selection than by neutrality.
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[效力级别]  [学科分类] 医学(综合)
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