SEGREGATION ANALYSES AND GENE-CENTROMERE DISTANCES IN ZEBRAFISH

[摘要] The gol-1, gol-2, alb-1 and spa-1 mutations affect pigment pattern in the zebrafish. We show here that these loci are unlinked to each other. In addition, gene-centromere distances were determined for these loci by analysis of halftetrads obtained by the inhibition of the second meiotic division. The fractions of tetratype (second-division segregation) tetrads range from 0.24 ( spa-1 ) to 0.89 ( gol-1 ). The observation of >0.67 second-division segregation indicates that the zebrafish has high chiasma interference.

[学科分类] 医学（综合）