MATERNAL AND ZYGOTIC INTERACTIONS BETWEEN THE ABNORMAL OOCYTE MUTATION AND THE SCUTE4 INVERSION IN DROSOPHILA MELANOGASTER

[摘要] The authors have studied the interaction between the abnormal oocyte mutation and an inversion of the X chromosome, In ( 1 ) sc 4, which has a proximal breakpoint in or near the heterochromatic region (ABO) that maternally interacts with the abo product. It has been demonstrated that the presence of X chromosomes carrying this inversion, besides a marked increase in the severity of the maternal effect of the abo mutation, produces a zygotic effect resulting in the lethality of the progeny of stocks homozygous for abo and sc 4. These results indicate that the sc 4 inversion carries an abnormal region indispensable for the development of abo zygotes from sc 4; abo mothers.

[学科分类] 医学（综合）