IS THE NOTCH LOCUS OF DROSOPHILA MELANOGASTER A TANDEM REPEAT? CORRELATION OF THE GENETIC MAP AND COMPLEMENTATION PATTERN OF SELECTED MUTATIONS

[摘要] Correlation of the complementation relationships between the Notch locus alleles fag, fano, Ax59d and nd , with their genetic map order, suggests a tandem repetition within the locus of functionally related sites. This observation is discussed in relation to two hypotheses: (1) that the Notch locus contains a tandem repeat of genetic material; and (2) that the tertiary structure of the Notch locus product has a spiral configuration.

[学科分类] 医学（综合）