DIVERGENT OPERONS AND THE GENETIC STRUCTURE OF THE MALTOSE B REGION IN ESCHERICHIA COLI K12

[摘要] Complementation and polarity suppression data are interpreted in terms of the genetic structure of the maltose B region. It is proposed that this region comprises two divergent operons. One operon includes mal K, a cistron involved in maltose permeation, and lam B the only known cistron specifically involved in λ receptor synthesis. The other operon includes mal J1 and mal J2 which are most probably two different cistrons, both involved in maltose permeation*. It is further assumed that expression of the two operons is controlled by mal T, the positive regulatory gene of the maltose system, located in the mal A region. The target(s) for the action of the mal T product is (are) most likely to be located between mal J1 and mal K. There is an indication that the two operons might overlap in the region of their promoters. The structure of such an overlap as well as the possible function of the products of the different cistrons in mal B are briefly discussed.

[学科分类] 医学（综合）