THE BACILLUS SUBTILIS GENOME: REPLICATION-ORDER AND MAP-POSITION DISCREPANCIES—EVIDENCE FOR A SECOND ORIGIN

[摘要] Replication order to map position discrepancies have been documented in B. subtilis . The discrepancies were found to occur whenever the genome of B. subtilis was replicated under a variety of physiological conditions and in both 168 and W23 strains. The earliest replicating marker involved in these discrepancies was thr versus pur B and aro A versus rec A. A detailed linkage analysis of the ura to arg A region was consistent with its being a continuous linkage group. This led to the conclusion that an origin for new starts at replication exists between rec A and aro A.

[学科分类] 医学（综合）