The Role of Potassium Ions in Angiotensin II-Stimulated Aldosterone Synthesis

[摘要] Angiotensin II (AII) stimulation of aldosterone synthesis entails depolarisation of the zona glomerulosa (ZG) cells. Since the ZG membrane potential is known to depend on the membrane permeability to potassium ions (K+), this study investigated the relationship between 43K efflux from freshly-isolated bovine ZG cells and basal and AII-stimulated aldosterone release.

[发布机构] University:University of Glasgow

[关键词] Molecular biology, Endocrinology