Energy Expenditure and Substrate Metabolism in Patients With Cancer and Weight Loss

[摘要] Cachexia is commonly seen in patients with cancer, and there is evidence to suggest that these debilitated cancer patients are at an increased risk of morbidity and mortality following surgical procedures. This thesis is concerned with two main avenues of investigation. In the first part, various mechanisms implicated in the development of cancer cachexia have been investigated in weight stable and weight losing patients with cancer and nonmalignant illness. The second part is concerned with ways of influencing the metabolic response in cancer patients undergoing moderate and major surgical procedures.

[发布机构] University:University of Glasgow

[关键词] Medicine, Oncology