In VitroRNA-dependent RNA Synthesis by a Curde Enzyme Fraction Isolated from Normal Rat Livers

[摘要] References(21)A crude enzyme preparation from "uninfected" rat livers can catalyze the synthesis of RNA when rat liver mRNA or nuclear RNA is added to the system. The newly synthesized RNA contains sequences comple-mentary to those of the RNA template and, after phenol extraction, is found to be partially hydrogen-bonded to the added poly (A)-containing RNA. The possibility of message amplification in normal cells is discussed.

[学科分类] 分子生物学，细胞生物学和基因