MICROPUNCTURE STUDY OF DISTAL TUBULAR FUNCTION OF CAT KIDNEY

[摘要] References(14)Micropuncture studies of the tubules accesible on the surface of the mammalian kidney have been performed usually in the rat, dog and monkey. The tubular fluid from early distal tubule in the rat was always hypotonic to plasma (1), but it reached isotonic to plasma in the late portion of the distal tubule (2-5). In contrast to the observation in the rat, it has been demonstrated that the tubular fluid was markedly hypotonic to plasma along the entire length of the distal tubule in the dog during antidiuretic as well as diuretic state (6, 7). In the kidney of the rhesus monkey, the distal tubular fluid was also hypotonic to plasma during hydropenia (8). The fact mentioned above has suggested that the distal tubular function of the rat kidney was different from that of the dog and monkey kidney. The micropuncture study of the cat kidney has not been reported. The present study was designed to investigate the pattern of the tubular function of the cat kidney.

[学科分类] 药理学