EFFECT OF 2-CHLORO-11 (4'-METHYL) PIPERAZINO -DIBENZO (b, f) (1, 4)-THIAZEPINE ON SOMATIC REFLEXES IN CAT

[摘要] References(13)Pharmacological properties of a potent neuroleptic agent, 2-chloro-ll-(4'-methyl) piperazino-dibenzo (b, f) (1, 4)-thiazepine (HF-2159) have been described by Stille et al. (1). Its profile of activity is in between chlorpromazine and haloperidol, both of which have marked effects on somatic reflexes (2-6). The present investigation has been undertaken to study the effect of HF-2159 on the somatic reflexes integrated at the spinal and the supraspinal level. Preliminary results of this study have appeared (7).

[学科分类] 药理学