EFFECT OF DOPA ON THE CATECHOLAMINE CONTENT OF DOG HEART AFTER HEMORRHAGIC HYPOTENSION

[摘要] References(22)After hemorrhagic hypotension in dogs, myocardial norepinephrine synthesis and storage were apparently disturbed. Dibenzyline seemed to prevent death of animals subjected to hemorrhagic hypotension by causing a reduction in the bleeding volume. However, dibenzyline did not prevent a fall in arterial blood pressure during DOPA infusion after hemorrhagic hypotension. It is suggested that fundamental damage occurred during hemorrhagic hypotension, which caused the depletion of myocardial norepinephrine content, and also produced cardiovascular failure.

[学科分类] 药理学