CARDIAC EFFECTS OF ANTIDEPRESSANTS

[摘要] References(18)Cited-By(18)The present study was undertaken to investigate the cardiac effects of 5 antidepressive tricyclic derivatives namely imipramine, desipramine, amitriptyline, trimeprimine and noxiptiline (Fig. 1). The following parameters were studied: 1) In vivo: Effects on ECG, their anti-arrhythmic and anticoronarospastic activity. 2) In vitro: Effects on the inotropism, chronotropism and coronary flow.

[学科分类] 药理学