ROLE OF CATECHOLAMINES IN THE MEDIATION OF PERIPHERAL EFFECTS OF FEMALE SEX HORMONES

[摘要] References(15)The effect of diethylstilboestrol (DES; 0.5 mg/100 g) and progesterone (2.5 mg/100 g) was studied on the catecholamine content of adrenals and uteri of seven day ovariectomized albino rats. The agents were administered i.p. on alternate days for one week and the tissue catecholamine content was determined spectrophotofluorometrically. DES treatment increased the total adrenaline contents of adrenals and uterus. On the other hand progesterone caused a decrease in the level of catecholamines in both the tissues. These findings are discussed in relation to the actions of female sex hormones on cardiovascular and genital systems.

[学科分类] 药理学