PHARMACOKINETIC STUDIES ON THE HEPATOTOXICITY OF LUTEOSKYRIN. (1) INTRACELLULAR DISTRIBUTION OF RADIOACTIVITY IN THE LIVER OF MICE ADMINISTERED 3H-LUTEOSKYRIN

[摘要] References(17)Cited-By(9)Intracellular distribution of the radioactivity derived from 3H-luteoskyrin in mouse liver was investigated. It was revealed that luteoskyrin has a high affinity to mitochondria and cell debris of mouse liver cells. This characteristic distribution pattern in the liver cells may be responsible for the mitochondrial impairment and the age and sex differences in the susceptibility of mice to this mycotoxin.

[学科分类] 药理学