POTENTIATION OF OXYTOCIN AND PROSTAGLANDINS-EVOKED RESPONSES BY (+) INPEA ON ISOLATED RAT UTERUS: ITS SPECIFICITY AND SELECTIVITY

[摘要] References(22)Cited-By(2)The effect of (+) INPEA on various stimulant drugs was examined on isolated rat uterus. Addition of (+) INPEA (1 × 10-5 g/ml) to the organ bath, produced marked potentiation in the contractile responses of oxytocin and prostaglandins. Potentiation was less significant to 5-HT, vasopressin, angiotensin and bradykinin. (+) INPEA did not potentiate the responses of oxytocin on isolated rat mammary strip and the responses of prostaglandins on rat stomach (fundus) strip, guinea-pig tracheal chain and guinea-pig ileum. The significance of these findings has been discussed.

[学科分类] 药理学