Involvement of Inhibitory Innervation in Reflex Tracheal Dilatation Induced by Lung Inflation

[摘要] References(12)Cited-By(2)We investigated the involvement of inhibitory innervation in reflex tracheal dilatation (RTD) induced by inflating the lungs in dogs. RTD was inhibited about 50% by 100 μg propranolol injected into the cranial thyroid artery, but was unaffected by adrenalectomy. Residual RTD under β-blockade was abolished by sections of both the bilateral superior laryngeal nerves and spinal cord at the C1 level. These findings suggest that RID may be mediated by adrenergic innervation and partly by nonadrenergic inhibitory innervation.

[学科分类] 药理学