Electrochemical biosensor-based devices for continuous phenols monitoring in environmental matrices

[摘要] The release of phenol and its chlorinated derivatives into the environmental is of great concern. A considerable number of organic pollutants, widely distributed throughout the environment, have a phenolic structure. Thus, there is a continuously increasing demand for selective and sensitive detection of phenols since these toxic compounds are widely used in the manufacture of various industrial products1,2 and they are known to be widespread as components of industrial waste.3,4 Phenolic compounds are a class of polluting chemicals, easily absorbed by animals and humans through the skin and mucous membranes.5 Their toxicity is directly towards a great variety of organs and tissues, primarily lungs, liver, kidneys and genito-urinary system.5,6 Many phenols, especially chlorophenols, are known for their persistency in the environment and propensity for bioconcentration and biomagnification.7 Several procedures have been developed for the determination of phenolic compounds, such as chromotographic techniques, fluorimetric and spectrophotometric methods.6,8 However, these techniques do not easily allow continuous monitoring in real samples. They are expensive, time-consuming, need skilled operators, and sometimes require preconcentration and extraction steps that increase the risk of samples loss.9,10 Biosensors represent promising tools to supplement already existing techniques, due to their intrinsic characteristics such as selectivity, low cost, potential for miniaturization/automation, and for the construction of simple flow devices for fast continuous monitoring.11 Lac

[学科分类] 化学（综合）