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Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A
[摘要] Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range.
[发布日期]  [发布机构] 
[效力级别]  [学科分类] 化学(综合)
[关键词] resorcinolic lipid;cytosporone A;allelopathic activity. [时效性] 
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