Antibacterial Activity of B-Cyclodextrin and 2-Hydroxypropyl-B-Cyclodextrin Trimethoprim Complexes | Science Publications

[摘要] Cyclodextrin complexation has previously been shown to improve the solubility and dissolution properties of trimethoprim; however, no report provides an account of the effect cyclodextrin complexation has on the antibacterial activity of this agent

[学科分类] 微生物学和免疫学

[关键词] Antibacterial activity;trimethoprim;2-hydroxypropyl;B-cyclodextrin;inclusion complex;antimicrobial activity;caco-2 cells;Differential Scanning Calorimetry (DSC)