Problem statement: Systems biology is an emerging field of science. The branch of system science was conceived and proposed by a biologist at the very beginning, at the conceptual birth of the branch. Systems biology a holistic approach to biology, still remains a field less opted by researchers and science personnels in general. Conclusion/Recommendations: In this review, we try to revisit this intriguing branch science since its birth in order draw the attention of the science professionals at large.
