Population susceptibility to a variant swine-origin influenza virus A(H3N2) in Vietnam, 2011�?2012

[摘要] SUMMARYA reassortant swine-origin A(H3N2) virus (A/swine/BinhDuong/03-9/2010) was detected through swine surveillance programmes in southern Vietnam in 2010. This virus contains haemagglutinin and neuraminidase genes from a human A(H3N2) virus circulating around 2004�?2006, and the internal genes from triple-reassortant swine influenza A viruses (IAVs). To assess population susceptibility to this virus we measured haemagglutination inhibiting (HI) titres to A/swine/BinhDuong/03-9/2010 and to seasonal A/Perth/16/2009 for 947 sera collected from urban and rural Vietnamese people during 2011�?2012. Seroprevalence (HI �? 40) was high and similar for both viruses, with 62·6% [95% confidence interval (CI) 59·4�?65·7] against A/Perth/16/2009 and 54·6% (95% CI 51·4�?57·8%) against A/swine/BinhDuong/03-9/2010, and no significant differences between urban and rural participants. Children aged

[学科分类] 流行病学