Craniospinal irradiation in an older patient

[摘要] We describe central nervous system blast crisis on a background of chronic myeloid leukaemia in remission in a 70-year-old man. After successful elimination of blasts in the cerebrospinal fluid, this patient received craniospinal irradiation (CSI). He remains well 30 months after CSI and has no significant long-term toxicity. CSI is usually reserved for patients under the age of 50 years and we wish to document its safe and successful use in this older patient.

[学科分类] 传染病学

[关键词] Craniospinal irradiation;chronic myeloid leukaemia;blast crisis;acute lymphoblastic leukaemia;adult