Devic’s disease associated with anti-Ro/SSA antibodies

[摘要] Neuromyelitis optica (NMO) and systemic inflammatory diseases are not mutually exclusive. Even when other autoantibodies are present, myelitis extending over 3 vertebral segments with NMO-IgG positivity discloses the diagnosis of NMO. We report the case of an isolated myelitis extending over 6 vertebral segments due to neuromyelitis optica (NMO). Despite the absence of optic nerve involvement, the absence of NMO-IgG in the blood and the presence of symptoms and autoantibodies suggestive of Sjögren syndrome, the diagnosis was founded on spinal magnetic resonance imaging and the detection of NMO-IgG specific antibodies in cerebrospinal fluid.

[学科分类] 传染病学

[关键词] Devic;neuromyelitis optica;aquaporin-4;Sjögren syndrome;antinuclear antibodies;anti-Ro/SSA