Rising Prostate-Specific Antigen Level After Prostatectomy

[摘要] A 57-year-old man was referred to his urologist after a routine serum prostate-specific antigen (PSA) test revealed a level of 9.4 ng/mL. The patient denied any significant lower urinary tract voiding symptoms. He was sexually potent and denied any family history of prostate cancer. Urine dip analysis showed no evidence of hematuria or urinary tract infection. Digital rectal examination revealed a 30-g prostate without induration or nodularity. Because of the elevated serum PSA level, the patient underwent transrectal, systematic sextant, ultrasound-guided prostate biopsies at an outside urologist’s clinic. The biopsies were sent for pathologic analysis as site-specifically labeled samples. Of the 6 cores obtained, the right-sided cores at the mid-prostate and apical prostate revealed Gleason 8 (4 + 4) adenocarcinoma. The maximum length of cancer was 6 mm, or 50% of the apical core.

[学科分类] 基础医学