Androgen Replacement Therapy and Prostate Cancer: Is Androgen Replacement Safe in High-Risk Patients?

[摘要] As our population grows older, ever-greater attention is being focused on therapies aimed at forestalling negative effects of the aging process. Prominent in this regard is androgen replacement in the aging man. Numerous publications have documented the potential benefit of testosterone supplementation among hypogonadal men. Conditions such as decreased bone density, loss of muscle mass and strength, increased adipose tissue, loss of sexual function, and mood disorders may, to some extent, be ameliorated through androgen replacement therapy. Equal attention, however, has been focused on the potential for deleterious effects to arise from androgen supplementation.

[学科分类] 基础医学