Fertility

[摘要] One of the difficult aspects of treating infertile men is that there are no recommended medical therapies for men with idiopathic oligospermia. This applies to the drug clomiphene citrate (CC). Although CC has at times been used empirically to treat men with idiopathic oligospermia, stringent, randomized, blinded, placebo-controlled trials demonstrating the efficacy of CC are lacking. As a result, physicians treating male infertility are always hopeful that some compound, which may have been associated with sperm function, will turn out to be the successful medication they have been searching for. One such compound that has captured the imagination is carnitine, which may have a number of different functions associated with sperm function (eg, support of mitochondrial function and serving as an antioxidant within sperm). Some studies have suggested that carnitine may be reduced in the semen of infertile men, and uncontrolled studies added fuel to the fire by demonstrating that oral carnitine seemed to improve sperm motility in men with low sperm motility.

[学科分类] 基础医学