Botulinum Toxin A in the Treatment of Neurogenic and Idiopathic Urinary Incontinence

[摘要] Anticholinergic therapy has long been considered the “gold standard” for treating urinary incontinence (UI) of both neurogenic and idiopathic origins. However, for those who fail this conservative measure for lack of efficacy or intolerable side effects, second-line treatments such as intradetrusor injections of botulinum toxin type A (BoNTA) have been studied. Initial studies have shown BoNTA to be of benefit clinically, as demonstrated by improvement in incontinence urodynamically as well as by quality-of-life (QOL) assessment.

[学科分类] 基础医学