Congenital Bladder Abnormalities

[摘要] Higuchi and colleagues from the Mayo Clinic (Rochester, MN) published an interesting study to determine if ileal/colonic bladder augmentation in patients with congenital bladder abnormalities such as myelomeningocele, bladder exstrophy, or posterior urethral valves is an independent risk factor for bladder malignancy.1 These entities may have an inherent risk of neoplastic transformation in the absence of bladder augmentation. Records were reviewed from 1986 to 2010. Follow-up from augmentation (109 ileal and 44 colonic) was for at least 10 years with a median interval of 27 years. Controls were treated with clean intermittent catheritization and anticholinergic medications and were matched with the augmentation group for bladder dysfunction, sex, and age.

[学科分类] 基础医学