Opsoclonus Myoclonus

[摘要] Opsoclonus myoclonus is a rare autoimmune condition characterized by cerebellar degeneration. It occurs most often as a paraneoplastic syndrome when a cancer remote to the brain induces cerebellar dysfunction that is unrelated to metastases. Half of all cases occur in children with a neuroblastoma. Most adults with opsoclonus myoclonus have neoplastic, infectious, metabolic, or idiopathic etiologies. Signs of cerebellar dysfunction noted at presentation include opsoclonus, myoclonus and ataxia, hence the name “dancing eyes, dancing feet syndrome.” Opsoclonus is characterized by rapid, involuntary eye movements that are dysrhythmic and uncoordinated.

[学科分类] 精神健康和精神病学

[关键词] Opsoclonus myoclonus;dancing eyes;dancing feet syndrome;paraneoplastic;autoimmune;cerebellar toxicity;cerebellar signs;opsoclonus